A prognostic signature of defective p53-dependent G1 checkpoint function in melanoma cell lines

Melanoma cell lines and normal human melanocytes were assayed for p53-dependent G1 checkpoint response to ionizing radiation-induced DNA damage. Sixty six percent of melanoma cell lines displayed a defective G1 checkpoint. Checkpoint function was correlated with sensitivity to ionizing radiation wit...

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Detalhes bibliográficos
Main Authors: Carson, Craig, Omolo, Bernard, Chu, Haitao, Zhou, Yingchun, Sambade, Maria J., Peters, Eldon C., Tompkins, Patrick, Simpson, Dennis A., Thomas, Nancy E., Fan, Cheng, Sarasin, Alain, Dessen, Philippe, Shields, Janiel M., Ibrahim, Joseph G., Kaufmann, William K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397470/
https://ncbi.nlm.nih.gov/pubmed/22540896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2012.01010.x
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