Defective Cell Cycle Checkpoint Functions in Melanoma Are Associated with Altered Patterns of Gene Expression

Defects in DNA damage responses may underlie genetic instability and malignant progression in melanoma. Cultures of normal human melanocytes (NHMs) and melanoma lines were analyzed to determine whether global patterns of gene expression could predict the efficacy of DNA damage cell cycle checkpoints...

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Detalhes bibliográficos
Main Authors: Kaufmann, William K., Nevis, Kathleen R., Qu, Pingping, Ibrahim, Joseph G., Zhou, Tong, Zhou, Yingchun, Simpson, Dennis A., Helms-Deaton, Jennifer, Cordeiro-Stone, Marila, Moore, Dominic T., Thomas, Nancy E., Hao, Honglin, Liu, Zhi, Shields, Janiel M., Scott, Glynis A., Sharpless, Norman E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753794/
https://ncbi.nlm.nih.gov/pubmed/17597816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jid.5700935
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