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A prognostic signature of defective p53-dependent G1 checkpoint function in melanoma cell lines
Melanoma cell lines and normal human melanocytes were assayed for p53-dependent G1 checkpoint response to ionizing radiation-induced DNA damage. Sixty six percent of melanoma cell lines displayed a defective G1 checkpoint. Checkpoint function was correlated with sensitivity to ionizing radiation wit...
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| Autors principals: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397470/ https://ncbi.nlm.nih.gov/pubmed/22540896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2012.01010.x |
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