Engineered Monoclonal Antibody with Novel Antigen-Sweeping Activity In Vivo

Monoclonal antibodies are widely used to target disease-related antigens. However, because conventional antibody binds to the antigen but cannot eliminate the antigen from plasma, and rather increases the plasma antigen concentration by reducing the clearance of the antigen, some clinically importan...

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Библиографические подробности
Главные авторы: Igawa, Tomoyuki, Maeda, Atsuhiko, Haraya, Kenta, Tachibana, Tatsuhiko, Iwayanagi, Yuki, Mimoto, Futa, Higuchi, Yoshinobu, Ishii, Shinya, Tamba, Shigero, Hironiwa, Naoka, Nagano, Kozue, Wakabayashi, Tetsuya, Tsunoda, Hiroyuki, Hattori, Kunihiro
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646756/
https://ncbi.nlm.nih.gov/pubmed/23667591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063236
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