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Calcium-dependent antigen binding as a novel modality for antibody recycling by endosomal antigen dissociation
The pH-dependent antigen binding antibody, termed a recycling antibody, has recently been reported as an attractive type of second-generation engineered therapeutic antibody. A recycling antibody can dissociate antigen in the acidic endosome, and thus bind to its antigen multiple times. As a consequ...
में बचाया:
| में प्रकाशित: | MAbs |
|---|---|
| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Taylor & Francis
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966519/ https://ncbi.nlm.nih.gov/pubmed/26496237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1110660 |
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