Engineering the variable region of therapeutic IgG antibodies

Since the first generation of humanized IgG1 antibodies reached the market in the late 1990s, IgG antibody molecules have been extensively engineered. The success of antibody therapeutics has introduced severe competition in developing novel therapeutic monoclonal antibodies, especially for promisin...

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Detaylı Bibliyografya
Asıl Yazarlar: Igawa, Tomoyuki, Tsunoda, Hiroyuki, Kuramochi, Taichi, Sampei, Zenjiro, Ishii, Shinya, Hattori, Kunihiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2011
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149705/
https://ncbi.nlm.nih.gov/pubmed/21406966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.3.15234
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