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Engineering the variable region of therapeutic IgG antibodies
Since the first generation of humanized IgG1 antibodies reached the market in the late 1990s, IgG antibody molecules have been extensively engineered. The success of antibody therapeutics has introduced severe competition in developing novel therapeutic monoclonal antibodies, especially for promisin...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149705/ https://ncbi.nlm.nih.gov/pubmed/21406966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.3.15234 |
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