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PI4P And PI(4,5)P(2) Are Essential But Independent Lipid Determinants Of Membrane Identity

The quantitatively minor phospholipid phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P(2)] fulfils many cellular functions in the plasma membrane (PM), whereas its major synthetic precursor, phosphatidylinositol 4-phosphate (PI4P), has no assigned PM roles apart from PI(4,5)P(2) synthesis. We used...

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Bibliografiska uppgifter
Huvudupphovsmän:	Hammond, Gerald R. V., Fischer, Michael J, Anderson, Karen E, Holdich, Jon, Koteci, Ardita, Balla, Tamas, Irvine, Robin F.
Materialtyp:	Artigo
Språk:	Inglês
Publicerad:	2012
Ämnen:	Article
Länkar:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3646512/ https://ncbi.nlm.nih.gov/pubmed/22722250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1222483
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PI4P And PI(4,5)P(2) Are Essential But Independent Lipid Determinants Of Membrane Identity

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