Probing the regulation of TASK potassium channels by PI(4,5)P(2) with switchable phosphoinositide phosphatases

ABSTRACT: TASK channels are background K(+) channels that contribute to the resting conductance in many neurons. A key feature of TASK channels is the reversible inhibition by Gq-coupled receptors, thereby mediating the dynamic regulation of neuronal activity by modulatory transmitters. The mechanis...

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Main Authors: Lindner, Moritz, Leitner, Michael G, Halaszovich, Christian R, Hammond, Gerald R V, Oliver, Dominik
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2011
Ábhair:
Neuroscience
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145931/
https://ncbi.nlm.nih.gov/pubmed/21540350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.208983
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