A method to control phosphoinositides and to analyze PTEN function in living cells using voltage sensitive phosphatases

Voltage sensitive phosphatases (VSPs), including engineered voltage sensitive PTEN, are excellent tools to rapidly and reversibly alter the phosphoinositide (PI) content of the plasma membrane in vivo and study the tumor suppressor PTEN. However, widespread adoption of these tools is hampered by the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Mavrantoni, Angeliki, Thallmair, Veronika, Leitner, Michael G., Schreiber, Daniela N., Oliver, Dominik, Halaszovich, Christian R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2015
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379879/
https://ncbi.nlm.nih.gov/pubmed/25873899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00068
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg