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PI4P And PI(4,5)P(2) Are Essential But Independent Lipid Determinants Of Membrane Identity
The quantitatively minor phospholipid phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P(2)] fulfils many cellular functions in the plasma membrane (PM), whereas its major synthetic precursor, phosphatidylinositol 4-phosphate (PI4P), has no assigned PM roles apart from PI(4,5)P(2) synthesis. We used...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3646512/ https://ncbi.nlm.nih.gov/pubmed/22722250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1222483 |
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