A small molecule compound identified through a cell-based screening inhibits JAK/STAT pathway signaling in human cancer cells

Inappropriate activation of JAK/STAT signaling occurs with high frequency in human cancers, and is associated with cancer cell survival and proliferation. Therefore, the development of pharmacological STAT signaling inhibitors has therapeutic potential in the treatment of human cancers. Here, we rep...

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Detaylı Bibliyografya
Asıl Yazarlar: Kim, Byung Hak, Yin, Chang-Hong, Guo, Qianxu, Bach, Erika A., Lee, Haeryun, Sandoval, Claudio, Jayabose, Somasundaram, Ulaczyk-Lesanko, Agnieszka, Hall, Dennis G., Baeg, Gyeong-Hun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646365/
https://ncbi.nlm.nih.gov/pubmed/18790749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0309
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