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A small molecule compound identified through a cell-based screening inhibits JAK/STAT pathway signaling in human cancer cells
Inappropriate activation of JAK/STAT signaling occurs with high frequency in human cancers, and is associated with cancer cell survival and proliferation. Therefore, the development of pharmacological STAT signaling inhibitors has therapeutic potential in the treatment of human cancers. Here, we rep...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3646365/ https://ncbi.nlm.nih.gov/pubmed/18790749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0309 |
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