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Development of a high-throughput cell-based reporter assay for screening JAK3 inhibitors
JAK3 has become an ideal target for the therapeutic treatment of immune-related diseases, as well as for the prevention of organ allograft rejection. A number of JAK3 inhibitors have been identified by in vitro biochemical enzymatic assays, but the majority display significant off-target effects on...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3237679/ https://ncbi.nlm.nih.gov/pubmed/21393628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057111400190 |
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