Atypical Melanocytic Proliferations and New Primary Melanomas in Patients With Advanced Melanoma Undergoing Selective BRAF Inhibition

PURPOSE: Selective inhibition of mutant BRAF by using class I RAF inhibitors in patients with metastatic melanoma has resulted in impressive clinical activity. However, there is also evidence that RAF inhibitors might induce carcinogenesis or promote tumor progression via stimulation of MAPK signali...

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Autores principales: Zimmer, Lisa, Hillen, Uwe, Livingstone, Elisabeth, Lacouture, Mario E., Busam, Klaus, Carvajal, Richard D., Egberts, Friederike, Hauschild, Axel, Kashani-Sabet, Mohammed, Goldinger, Simone M., Dummer, Reinhard, Long, Georgina V., McArthur, Grant, Scherag, André, Sucker, Antje, Schadendorf, Dirk
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Clinical Oncology 2012
Materias:
Original Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646308/
https://ncbi.nlm.nih.gov/pubmed/22614973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.41.1660
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