Atypical Melanocytic Proliferations and New Primary Melanomas in Patients With Advanced Melanoma Undergoing Selective BRAF Inhibition

PURPOSE: Selective inhibition of mutant BRAF by using class I RAF inhibitors in patients with metastatic melanoma has resulted in impressive clinical activity. However, there is also evidence that RAF inhibitors might induce carcinogenesis or promote tumor progression via stimulation of MAPK signali...

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Bibliographische Detailangaben
Hauptverfasser: Zimmer, Lisa, Hillen, Uwe, Livingstone, Elisabeth, Lacouture, Mario E., Busam, Klaus, Carvajal, Richard D., Egberts, Friederike, Hauschild, Axel, Kashani-Sabet, Mohammed, Goldinger, Simone M., Dummer, Reinhard, Long, Georgina V., McArthur, Grant, Scherag, André, Sucker, Antje, Schadendorf, Dirk
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2012
Schlagworte:
Original Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646308/
https://ncbi.nlm.nih.gov/pubmed/22614973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.41.1660
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