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A20 Restricts Wnt Signaling in Intestinal Epithelial Cells and Suppresses Colon Carcinogenesis

Colon carcinogenesis consists of a multistep process during which a series of genetic and epigenetic adaptations occur that lead to malignant transformation. Here, we have studied the role of A20 (also known as TNFAIP3), a ubiquitin-editing enzyme that restricts NFκB and cell death signaling, in int...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shao, Ling, Oshima, Shigeru, Duong, Bao, Advincula, Rommel, Barrera, Julio, Malynn, Barbara A., Ma, Averil
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645994/
https://ncbi.nlm.nih.gov/pubmed/23671587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062223
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