Folylpoly-Glutamate Synthetase Expression is associated with Tumor Response and Outcome from Pemetrexed-based Chemotherapy in Malignant Pleural Mesothelioma

PURPOSE: Pemetrexed-based chemotherapy represents the standard of care in firstline-treatment of advanced malignant pleural mesothelioma (MPM). However, there are no established predictors of clinical benefit. Pemetrexed inhibits multiple enzymes involved in pyrimidine and purine synthesis, but the...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Christoph, Daniel C., Asuncion, Bernadette Reyna, Mascaux, Celine, Tran, Cindy, Lu, Xian, Wynes, Murry W., Gauler, Thomas C., Wohlschlaeger, Jeremias, Theegarten, Dirk, Neumann, Volker, Hepp, Rodrigo, Welter, Stefan, Stamatis, Georgios, Tannapfel, Andrea, Schuler, Martin, Eberhardt, Wilfried E., Hirsch, Fred R.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645940/
https://ncbi.nlm.nih.gov/pubmed/22895141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318260deaa
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker