Significance of Folate Receptor alpha and Thymidylate Synthase Protein Expression in Patients with Non-Small Cell Lung Cancer treated with Pemetrexed

INTRODUCTION: Folate receptor alpha (FRA) regulates cellular uptake of folates and antifolates. Information about FRA protein expression in metastatic Non-Small Cell Lung Cancer (NSCLC) is limited. We investigated FRA as a biomarker for pemetrexed-based chemotherapy and compared it to thymidylate sy...

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Hauptverfasser: Christoph, Daniel C, Asuncion, Bernadette Reyna, Hassan, Biftu, Tran, Cindy, Maltzman, Julia D, O’Shannessy, Daniel J, Wynes, Murry W, Gauler, Thomas C, Wohlschlaeger, Jeremias, Hoiczyk, Mathias, Schuler, Martin, Eberhardt, Wilfried E, Hirsch, Fred R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645936/
https://ncbi.nlm.nih.gov/pubmed/23242435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31827628ff
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