Significance of Folate Receptor alpha and Thymidylate Synthase Protein Expression in Patients with Non-Small Cell Lung Cancer treated with Pemetrexed

INTRODUCTION: Folate receptor alpha (FRA) regulates cellular uptake of folates and antifolates. Information about FRA protein expression in metastatic Non-Small Cell Lung Cancer (NSCLC) is limited. We investigated FRA as a biomarker for pemetrexed-based chemotherapy and compared it to thymidylate sy...

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Detalhes bibliográficos
Main Authors: Christoph, Daniel C, Asuncion, Bernadette Reyna, Hassan, Biftu, Tran, Cindy, Maltzman, Julia D, O’Shannessy, Daniel J, Wynes, Murry W, Gauler, Thomas C, Wohlschlaeger, Jeremias, Hoiczyk, Mathias, Schuler, Martin, Eberhardt, Wilfried E, Hirsch, Fred R
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645936/
https://ncbi.nlm.nih.gov/pubmed/23242435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31827628ff
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