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Indoleamine 2,3-Dioxygenase and Dendritic Cell Tolerogenicity

This article summarizes the molecular and cellular mechanisms that regulate the activity of indoleamine 2,3-dioxygenase (IDO), a potent immune-suppressive enzyme, in dendritic cells (DCs). Specific attention is given to differential up-regulation of IDO in distinct DC subsets, its function in immune...

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Bibliografiske detaljer
Main Authors: Harden, Jamie L., Egilmez, Nejat K.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645912/
https://ncbi.nlm.nih.gov/pubmed/23017144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08820139.2012.676122
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