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Indoleamine-2,3-dioxygenase enzyme expression and activity in polarized dendritic cells
BACKGROUND AIMS: Polarized mature dendritic cells (DC) can activate cytolytic T-lymphocyte (CTL) responses and may be a more effective clinical strategy in DC-based cancer vaccines. A subset of mature DC can down-regulate the T-cell immune response through expression of indoleamine-2,3-dioxygenase (...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3786593/ https://ncbi.nlm.nih.gov/pubmed/19929471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14653240903271230 |
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