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Indoleamine-2,3-dioxygenase enzyme expression and activity in polarized dendritic cells

BACKGROUND AIMS: Polarized mature dendritic cells (DC) can activate cytolytic T-lymphocyte (CTL) responses and may be a more effective clinical strategy in DC-based cancer vaccines. A subset of mature DC can down-regulate the T-cell immune response through expression of indoleamine-2,3-dioxygenase (...

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Detalhes bibliográficos
Main Authors: Wolf, Benita, Posnick, David, Fisher, Jan L., Lewis, Lionel D., Ernstoff, Marc S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786593/
https://ncbi.nlm.nih.gov/pubmed/19929471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14653240903271230
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