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Dendritic cells, indoleamine 2,3 dioxygenase and acquired immune privilege

Dendritic cells (DCs) are specialized to stimulate T cell immunity. Paradoxically some DCs suppress T cell responses, and activate regulatory T cells. In this review we focus on a potent counter-regulatory pathway mediated by plasmacytoid DCs (pDCs) expressing the immunosuppressive enzyme indoleamin...

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Detalhes bibliográficos
Main Authors: Huang, Lei, Baban, Babak, Johnson, Burles A, Mellor, Andrew L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671384/
https://ncbi.nlm.nih.gov/pubmed/20367139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08830180903349669
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