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Indoleamine 2,3-dioxygenase (IDO) induced by Leishmania infection of human dendritic cells

Dendritic cells (DC) play a pivotal role in regulating immunity, establishing immunologically privileged tissue micro-environments and maintaining homeostasis. It is becoming increasingly clear that one key mechanism that mediates many DC functions is production of the immunomodulatory enzyme indole...

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Autors principals: Donovan, Michael J, Tripathi, Vinita, Favila, Michelle A., Geraci, Nicholas S., Lange, Marie C., Ballhorn, Wibke, McDowell, Mary Ann
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572781/
https://ncbi.nlm.nih.gov/pubmed/22803643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-3024.2012.01380.x
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