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GTPase-activating protein SH2-SH3 domains induce gene expression in a Ras-dependent fashion.

The p21ras GTPase-activating protein (GAP) is thought to function as both a negative regulator and a downstream target of p21ras. Here, we have investigated the role of GAP by using a transient expression assay with a fos luciferase reporter plasmid. We used GAP deletion mutants that lack the domain...

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Bibliographische Detailangaben
Hauptverfasser: Medema, R H, de Laat, W L, Martin, G A, McCormick, F, Bos, J L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC364591/
https://ncbi.nlm.nih.gov/pubmed/1321335
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