Insulin stimulation of gene expression mediated by p21ras activation.

In fibroblasts, insulin is a weak mitogen and does not induce expression of c-fos, c-jun or p33. However, increasing the expression levels of either normal p21Hras or the insulin receptor, but not mutant p21Hras, enables insulin to induce the expression of these genes. In cells expressing elevated l...

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Bibliografiske detaljer
Main Authors: Burgering, B M, Medema, R H, Maassen, J A, van de Wetering, M L, van der Eb, A J, McCormick, F, Bos, J L
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC452763/
https://ncbi.nlm.nih.gov/pubmed/2022184
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