Wird geladen...

Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis

Progression of solid tumors to the metastatic stage is accountable for the majority of cancer-related deaths. Further understanding of the molecular mechanisms governing metastasis is essential for the development of antimetastatic regimens. Here, we aimed to identify Rac activators that could promo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Laurin, Mélanie, Huber, Jennifer, Pelletier, Ariane, Houalla, Tarek, Park, Morag, Fukui, Yoshinori, Haibe-Kains, Benjamin, Muller, William J., Côté, Jean-François
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645577/
https://ncbi.nlm.nih.gov/pubmed/23592719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213050110
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!