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Phosphoregulation promotes release of kinetochores from dynamic microtubules via multiple mechanisms

During mitosis, multiprotein complexes called kinetochores orchestrate chromosome segregation by forming load-bearing attachments to dynamic microtubule tips, and by participating in phosphoregulatory error correction. The conserved kinase Aurora B phosphorylates the major microtubule-binding kineto...

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Hlavní autoři: Sarangapani, Krishna K., Akiyoshi, Bungo, Duggan, Nicole M., Biggins, Sue, Asbury, Charles L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645574/
https://ncbi.nlm.nih.gov/pubmed/23589891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220700110
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