Tension directly stabilizes reconstituted kinetochore-microtubule attachments

Kinetochores are macromolecular machines that couple chromosomes to dynamic microtubule tips during cell division, thereby generating force to segregate the chromosomes(1,2). Accurate segregation depends on selective stabilization of correct ‘bi-oriented’ kinetochore-microtubule attachments, which c...

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Autori principali: Akiyoshi, Bungo, Sarangapani, Krishna K., Powers, Andrew F., Nelson, Christian R., Reichow, Steve L., Arellano-Santoyo, Hugo, Gonen, Tamir, Ranish, Jeffrey A., Asbury, Charles L., Biggins, Sue
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108429/
https://ncbi.nlm.nih.gov/pubmed/21107429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09594
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