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The structure of purified kinetochores reveals multiple microtubule attachment sites
Chromosomes must be accurately partitioned to daughter cells to prevent aneuploidy, a hallmark of many tumors and birth defects. Kinetochores are the macromolecular machines that segregate chromosomes by maintaining load-bearing attachments to the dynamic tips of microtubules. Here, we present the s...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443262/ https://ncbi.nlm.nih.gov/pubmed/22885327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2358 |
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