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Phosphoregulation promotes release of kinetochores from dynamic microtubules via multiple mechanisms
During mitosis, multiprotein complexes called kinetochores orchestrate chromosome segregation by forming load-bearing attachments to dynamic microtubule tips, and by participating in phosphoregulatory error correction. The conserved kinase Aurora B phosphorylates the major microtubule-binding kineto...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3645574/ https://ncbi.nlm.nih.gov/pubmed/23589891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220700110 |
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