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Allosteric mechanisms can be distinguished using structural mass spectrometry
The activity of many proteins, including metabolic enzymes, molecular machines, and ion channels, is often regulated by conformational changes that are induced or stabilized by ligand binding. In cases of multimeric proteins, such allosteric regulation has often been described by the concerted Monod...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3645570/ https://ncbi.nlm.nih.gov/pubmed/23589876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302395110 |
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