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Allosteric mechanisms can be distinguished using structural mass spectrometry

The activity of many proteins, including metabolic enzymes, molecular machines, and ion channels, is often regulated by conformational changes that are induced or stabilized by ligand binding. In cases of multimeric proteins, such allosteric regulation has often been described by the concerted Monod...

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Detalhes bibliográficos
Main Authors: Dyachenko, Andrey, Gruber, Ranit, Shimon, Liat, Horovitz, Amnon, Sharon, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645570/
https://ncbi.nlm.nih.gov/pubmed/23589876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302395110
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