Chargement en cours...
Allosteric control of the ribosome by small-molecule antibiotics
Protein synthesis is targeted by numerous, chemically distinct antibiotics that bind and inhibit key functional centers of the ribosome. Using single-molecule imaging and X-ray crystallography, we show that the aminoglycoside neomycin blocks aminoacyl–transfer RNA (aa-tRNA) selection and translocati...
Enregistré dans:
| Auteurs principaux: | , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3645490/ https://ncbi.nlm.nih.gov/pubmed/22902368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2360 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|