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Hepatocyte nuclear factor 4α regulation of bile acid and drug metabolism
The hepatocyte nuclear factor 4α (HNF4α) is a liver-enriched nuclear receptor that plays a critical role in early morphogenesis, fetal liver development, liver differentiation and metabolism. Human HNF4α gene mutations cause maturity on-set diabetes of the young type 1, an autosomal dominant non-ins...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3645476/ https://ncbi.nlm.nih.gov/pubmed/19239393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425250802707342 |
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