Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4α

Hepatocyte nuclear factor 4α (HNF4α) regulates many genes that are preferentially expressed in liver. Mice lacking hepatic expression of HNF4α, HNF4α(ΔL), exhibited markedly elevated levels of serum bile acids compared to HNF4α-floxed mice, HNF4α(F/F). The expression of genes involved in the hydroxy...

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Autori principali: Inoue, Yusuke, Yu, Ai-Ming, Yim, Sun Hee, Ma, Xiaochao, Krausz, Kristopher W., Inoue, Junko, Xiang, Charlie C., Brownstein, Michael J., Eggertsen, Gösta, Björkhem, Ingemar, Gonzalez, Frank J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413576/
https://ncbi.nlm.nih.gov/pubmed/16264197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M500430-JLR200
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