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Hepatocyte nuclear factor 4α in the intestinal epithelial cells protects against inflammatory bowel disease
BACKGROUND: Hepatocyte nuclear factor 4α (HNF4α; NR2A1) is an orphan member of the nuclear receptor superfamily expressed in liver and intestine. While HNF4α expression is critical for liver function, its role in the gut and in the pathogenesis of inflammatory bowel disease (IBD) is unknown. METHODS...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435391/ https://ncbi.nlm.nih.gov/pubmed/18338782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.20413 |
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