Cholic acid mediates negative feedback regulation of bile acid synthesis in mice

Cholesterol is converted into dozens of primary and secondary bile acids through pathways subject to negative feedback regulation mediated by the nuclear receptor farnesoid X receptor (FXR) and other effectors. Disruption of the sterol 12α-hydroxylase gene (Cyp8b1) in mice prevents the synthesis of...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Li-Hawkins, Jia, Gåfvels, Mats, Olin, Maria, Lund, Erik G., Andersson, Ulla, Schuster, Gertrud, Björkhem, Ingemar, Russell, David W., Eggertsen, Gosta
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2002
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC150802/
https://ncbi.nlm.nih.gov/pubmed/12393855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI16309
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki