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Structure-Based Functional Design of Drugs: From Target to Lead Compound
Proteomic and genomic discoveries have identified vast numbers of new drug targets for investigation. In the quest to discover drugs that modulate the function of these targets, identification of small-molecule drug leads is one of the earliest steps. Structure-based drug design has emerged as a val...
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Format: | Artigo |
Jezik: | Inglês |
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2012
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Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644978/ https://ncbi.nlm.nih.gov/pubmed/22081357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-216-2_23 |
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