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Parkinson’s disease-associated mutations in DJ-1 modulate its dimerization in living cells
Mutations in the protein DJ-1 cause recessive forms of early onset familial Parkinson’s disease (PD). To date, most of the causative mutations studied destabilize formation of DJ-1 homodimers, which appears to be closely linked to its normal function in oxidative stress and other cellular processes....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644405/ https://ncbi.nlm.nih.gov/pubmed/23183826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-012-0976-y |
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