The Parkinson’s Disease-Linked Protein DJ-1 Associates with Cytoplasmic mRNP Granules During Stress and Neurodegeneration

Mutations in the gene encoding DJ-1 are associated with autosomal recessive forms of Parkinson’s disease (PD). DJ-1 plays a role in protection from oxidative stress, but how it functions as an “upstream” oxidative stress sensor and whether this relates to PD is still unclear. Intriguingly, DJ-1 may...

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Veröffentlicht in:Mol Neurobiol
Hauptverfasser: Repici, Mariaelena, Hassanjani, Mahdieh, Maddison, Daniel C., Garção, Pedro, Cimini, Sara, Patel, Bhavini, Szegö, Éva M., Straatman, Kornelis R., Lilley, Kathryn S., Borsello, Tiziana, Outeiro, Tiago F., Panman, Lia, Giorgini, Flaviano
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334738/
https://ncbi.nlm.nih.gov/pubmed/29675578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1084-y
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