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mRNP architecture in translating and stress conditions reveals an ordered pathway of mRNP compaction

Stress granules (SGs) are transient membraneless organelles of nontranslating mRNA–protein complexes (mRNPs) that form during stress. In this study, we used multiple single-molecule FISH probes for particular mRNAs to examine their SG recruitment and spatial organization. Ribosome runoff is required...

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Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Khong, Anthony, Parker, Roy
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279387/
https://ncbi.nlm.nih.gov/pubmed/30322972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201806183
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