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The Cellular EJC Interactome Reveals Higher Order mRNP Structure and an EJC-SR Protein Nexus

In addition to sculpting eukaryotic transcripts by removing introns, pre-mRNA splicing greatly impacts protein composition of the emerging mRNP. The exon junction complex (EJC), deposited upstream of exon-exon junctions after splicing, is a major constituent of spliced mRNPs. Here we report comprehe...

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Detalhes bibliográficos
Main Authors: Singh, Guramrit, Kucukural, Alper, Cenik, Can, Leszyk, John D., Shaffer, Scott A., Weng, Zhiping, Moore, Melissa J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522173/
https://ncbi.nlm.nih.gov/pubmed/23084401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.10.007
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