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Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals
Two major processes govern T cell proliferation and survival: interleukin-7-mediated homeostasis and antigen-induced selection. How cells transit between the two states is unknown. Here we show that T cell receptor ligation actively inhibits homeostatic survival signals while initiating a new, domin...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644093/ https://ncbi.nlm.nih.gov/pubmed/23591902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2719 |
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