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B Cell Antigen Receptor Signaling and Internalization Are Mutually Exclusive Events

Engagement of the B cell antigen receptor initiates two concurrent processes, signaling and receptor internalization. While both are required for normal humoral immune responses, the relationship between these two processes is unknown. Herein, we demonstrate that following receptor ligation, a small...

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Detalhes bibliográficos
Main Authors: Hou, Ping, Araujo, Elizabeth, Zhao, Tong, Zhang, Miao, Massenburg, Don, Veselits, Margaret, Doyle, Colleen, Dinner, Aaron R, Clark, Marcus R
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470458/
https://ncbi.nlm.nih.gov/pubmed/16719564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040200
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