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B Cell Antigen Receptor Signaling and Internalization Are Mutually Exclusive Events

Engagement of the B cell antigen receptor initiates two concurrent processes, signaling and receptor internalization. While both are required for normal humoral immune responses, the relationship between these two processes is unknown. Herein, we demonstrate that following receptor ligation, a small...

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Bibliografiske detaljer
Main Authors: Hou, Ping, Araujo, Elizabeth, Zhao, Tong, Zhang, Miao, Massenburg, Don, Veselits, Margaret, Doyle, Colleen, Dinner, Aaron R, Clark, Marcus R
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1470458/
https://ncbi.nlm.nih.gov/pubmed/16719564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040200
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