Evaluating Power and Type 1 Error in Large Pedigree Analyses of Binary Traits

Studying population isolates with large, complex pedigrees has many advantages for discovering genetic susceptibility loci; however, statistical analyses can be computationally challenging. Allelic association tests need to be corrected for relatedness among study participants, and linkage analyses...

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Detalhes bibliográficos
Main Authors: Cummings, Anna C., Torstenson, Eric, Davis, Mary F., D’Aoust, Laura N., Scott, William K., Pericak-Vance, Margaret A., Bush, William S., Haines, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643945/
https://ncbi.nlm.nih.gov/pubmed/23658753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062615
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