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Using linkage analysis of large pedigrees to guide association analyses

To date, genome-wide association studies have yielded discoveries of common variants that partly explain familial aggregation of diseases and traits. Researchers are now turning their attention to less common variants because the price of sequencing has dropped drastically. However, because sequenci...

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Détails bibliographiques
Auteurs principaux: Choi, Seung-Hoan, Liu, Chunyu, Dupuis, Josée, Logue, Mark W, Jun, Gyungah
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287919/
https://ncbi.nlm.nih.gov/pubmed/22373287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S79
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