Examination of Candidate Exonic Variants for Association to Alzheimer Disease in the Amish

Alzheimer disease (AD) is the most common cause of dementia. As with many complex diseases, the identified variants do not explain the total expected genetic risk that is based on heritability estimates for AD. Isolated founder populations, such as the Amish, are advantageous for genetic studies as...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: D’Aoust, Laura N., Cummings, Anna C., Laux, Renee, Fuzzell, Denise, Caywood, Laura, Reinhart-Mercer, Lori, Scott, William K., Pericak-Vance, Margaret A., Haines, Jonathan L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323242/
https://ncbi.nlm.nih.gov/pubmed/25668194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118043
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