Examination of Candidate Exonic Variants for Association to Alzheimer Disease in the Amish

Alzheimer disease (AD) is the most common cause of dementia. As with many complex diseases, the identified variants do not explain the total expected genetic risk that is based on heritability estimates for AD. Isolated founder populations, such as the Amish, are advantageous for genetic studies as...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: D’Aoust, Laura N., Cummings, Anna C., Laux, Renee, Fuzzell, Denise, Caywood, Laura, Reinhart-Mercer, Lori, Scott, William K., Pericak-Vance, Margaret A., Haines, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323242/
https://ncbi.nlm.nih.gov/pubmed/25668194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118043
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