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Erk1 and Erk2 are required for maintenance of hematopoietic stem cells and adult hematopoiesis
Extracellular signal-regulated kinase 1 (Erk1) and Erk2 play crucial roles in cell survival, proliferation, cell adhesion, migration, and differentiation in many tissues. Here, we report that the absence of Erk1 and Erk2 in murine hematopoietic cells leads to bone marrow aplasia, leukopenia, anemia,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3643760/ https://ncbi.nlm.nih.gov/pubmed/23444405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-476200 |
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