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Antagonism of Lidocaine Inhibition by Open-Channel Blockers That Generate Resurgent Na Current
Na channels that generate resurgent current express an intracellular endogenous open-channel blocking protein, whose rapid binding upon depolarization and unbinding upon repolarization minimizes fast and slow inactivation. Na channels also bind exogenous compounds, such as lidocaine, which functiona...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3643213/ https://ncbi.nlm.nih.gov/pubmed/23486968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3026-12.2013 |
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